Dr. Alberto S. Pappo 2007     Journal of the National Comprehensive Cancer Network NCCN Task Force Report: Management of Patients with Gastrointestinal Stromal Tumor (GIST) – Update of the NCCN Clinical practice Guidelines    13,343 KB 2005     Pediatric Blood & Cancer Clinical and Molecular Characteristics of Pediatric Gastrointestinal Stromal Tumors (GISTs)    204 KB 2004     Cancer Pediatric Gastrointestinal Stromal Tumors and Leiomyosarcoma    118 KB   Dr. Constantine Stratakis 2008     The American Journal of Human Genetics SNP Arrays in Heterogeneous Tissue: Highly Accurate Collection of Both Germline and Somatic Genetic Information from Unpaired Single Tumor Samples    807 KB 2007     The Journal of Clinical Endocrinology & Metabolism Genetics of Carney Triad: Recurrent Losses at Chromosome 1 but Lack of Germline Mutations in Genes Associated with Paragangliomas and Gastrointestinal Stromal Tumors    286 KB 2007     The Journal of Clinical Endocrinology & Metabolism Multiple Gastrointestinal Stromal and Other Tumors Caused by Platelet-Derived Growth Factor Receptor α Gene Mutations: A Case Associated with a Germline V561D Defect    469 KB 2007     The New England Journal of Medicine Familial Gastrointestinal Stromal Tumors and Germ-Line Mutations    265 KB 2007     European Journal of Human genetics Clinical and molecular genetics of patients with the Carney–Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD    413 KB 2006     American Journal of Surgical Pathology Functioning Paraganglioma and Gastrointestinal Stromal Tumor of the Jejunum in Three Women    1569 KB   Dr. Cristina R. Antonescu 2008     Modern Pathology Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases    366 KB 2008     Cancer Tumor Mitotic Rate, Size, and Location Independently Predict Recurrence After Resection of Primary Gastrointestinal Stromal Tumor (GIST)    201 KB 2008     Modern Pathology Targeted therapy of cancer: new roles for pathologists in identifying GISTs and other sarcomas    99 KB 2008     Genes, Chromosomes & Cancer Novel V600E BRAF Mutations in Imatinib-Naive and Imatinib-Resistant Gastrointestinal Stromal Tumors    462 KB 2008     Clinical Cancer Research Molecular Characterization of Pediatric Gastrointestinal StromalTumors    648 KB 2007     Clinical Cancer Research Sorafenib Inhibits the Imatinib-Resistant KITT670I Gatekeeper Mutation in Gastrointestinal Stromal Tumor    386 KB 2007     Annals of Surgery Results of Tyrosine Kinase Inhibitor Therapy Followed by Surgical Resection for Metastatic Gastrointestinal Stromal Tumor    685 KB 2006     Annals of Surgical Oncology Outcome of Metastatic GIST in the Era before Tyrosine Kinase Inhibitors    269 KB 2005     Journal of Pediatric Hematology/Oncology Gastrointestinal Stromal Tumors in Children and Young Adults    1085 KB 2004    Clinical Cancer Research Gene Expression in Gastrointestinal Stromal Tumors Is Distinguished by KIT Genotype and Anatomic Site    399 KB   Dr. George D. Demetri 2008     Journal of Clinical Oncology Correlation of Kinase Genotype and Clinical Outcome in the North American Intergroup Phase III Trial of Imatinib Mesylate for Treatment of Advanced Gastrointestinal Stromal Tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group    202 KB 2008     Oncogene Protein kinase C-θ regulates KIT expression and proliferation in gastrointestinal stromal tumors    570 KB 2008     Journal of Clinical Oncology Phase III Randomized, Intergroup Trial Assessing Imatinib Mesylate At Two Dose Levels in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing the Kit Receptor Tyrosine Kinase: S0033    197 KB 2007     Journal of the National Comprehensive Cancer Network NCCN Task Force Report: Management of Patients with Gastrointestinal Stromal Tumor (GIST) – Update of the NCCN Clinical practice Guidelines    13,343 KB 2007     Annals of Oncology Advances in the treatment of gastrointestinal stromal tumours    509 KB 2006     Lancet Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial    174 KB 2002     The New England Journal of Medicine Efficacy and safety of Imatinib Mesylate in advanced gastrointestinal stromal tumors    271 KB 2002     Human Pathology Clinical Management of Gastrointestinal Stromal Tumors: Before and After STI-571    174 KB   Dr. Katherine A. Janeway 2007     Clinical Cancer Research Pediatric KIT–Wild-Type and Platelet-Derived Growth Factor Receptor α –Wild-Type Gastrointestinal Stromal Tumors Share KIT Activation but not Mechanisms of Genetic Progression with Adult Gastrointestinal Stromal Tumors    283 KB   Dr. Jonathan C. Trent 2008     Annals of Surgical Oncology A Randomized, Phase II Study of Preoperative plus Postoperative Imatinib in GIST: Evidence of Rapid Radiographic Response and Temporal Induction of Tumor Cell Apoptosis    465 KB 2008     Cancer Genetic Aberrations of Gastrointestinal Stromal Tumors    130 KB 2008     Modern Pathology Evolution from heterozygous to homozygous KIT mutation in gastrointestinal stromal tumor correlates with the mechanism of mitotic nondisjunction and significant tumor progression    582 KB 2008     Ophthalmology Ulcerative Keratitis in Gastrointestinal Stromal Tumor Patients Treated with Perifosine    428 KB 2008     Journal of Clinical Investigation An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic    1,449 KB 2007     Clinical Cancer Research Association of IntratumoralVascular Endothelial Growth Factor Expression and Clinical Outcome for Patients with Gastrointestinal Stromal Tumors Treated with Imatinib Mesylate    278 KB 2007     International Journal of Cancer Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor    738 KB 2007     Proceedings of the National Academy of Sciences USA Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas    464 KB 2006     Cancer Hepatic Artery Chemoembolization for 110 Gastrointestinal Stromal Tumors    142 KB 2006     Annals of Surgical Oncology Surgical Resection of Gastrointestinal Stromal Tumors After Treatment with Imatinib    237 KB 2006     Cancer Correlation of Immunophenotype With Progression-Free Survival in Patients With Gastrointestinal Stromal Tumors Treated With Imatinib Mesylate    415 KB 2005     Expert Opinion on Pharmacotherapy Imatinib mesylate in the treatment of gastrointestinal stromal Tumour    223 KB 2005     Cancer Control Update on the Biology and Therapy of Gastrointestinal Stromal Tumors    236 KB 2004     Cancer Research A Missense Mutation in KIT Kinase Domain 1 Correlates with Imatinib Resistance in Gastrointestinal Stromal Tumors    756 KB   Dr. Margaret von Mehren 2008     Journal of Clinical Oncology Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing KIT    157 KB 2008    Current Opinion in Oncology The role of adjuvant and neoadjuvant therapy in gastrointestinal stromal tumors    84 KB 2008    Proceedings of the National Academy of Sciences USA Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors    545 KB 2008    Cell Cycle The insulin-like growth factor system as a potential therapeutic target in gastrointestinal stromal tumors    597 KB 2008    Journal of Clinical Oncology Correlation of Kinase Genotype and Clinical Outcome in the North American Intergroup Phase III Trial of Imatinib Mesylate for Treatment of Advanced Gastrointestinal Stromal Tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group    202 KB 2008    Journal of Surgical Oncology Phase II Trial of Neoadjuvant/Adjuvant Imatinib Mesylate (IM) for Advanced Primary and Metastatic/Recurrent Operable Gastrointestinal Stromal Tumor (GIST): Early Results of RTOG 0132/ACRIN 6665    125 KB 2008    Journal of Clinical Oncology Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing KIT    157 KB 2006    Journal of Clinical Oncology Molecular Correlates of Imatinib Resistance in Gastrointestinal Stromal Tumors    1,756 KB 2006    Cancer Research Therapeutic Effect of Imatinib in Gastrointestinal Stromal Tumors: AKT Signaling Dependent and Independent Mechanisms    609 KB 2005    Hematology/Oncology Clinics of North America Gastrointestinal Stromal Tumors    269 KB 2005    Clinical Cancer Research Analysis of KITMutations in Sporadic and Familial Gastrointestinal StromalTumors:Therapeutic Implications through ProteinModeling    791 KB   Dr. Michael P. LaQuaglia 2008     Clinical Cancer Research Molecular Characterization of Pediatric Gastrointestinal StromalTumors    648 KB 2006     Journal of Pediatric Hematology/Oncology Gastrointestinal Stromal Tumors in Children and Young Adults    1085 KB

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